Odds of Life Beyond Earth Go Way Up

Filed in Biotechnology | Science | Technology

NASA and the journal Nature made announcements this week which increase the odds of life beyond Earth significantly.

NASA’s announcement is the bigger of the two.  Scientist’s found life in California’s Mono Lake that is unlike all other known life on Earth.  Until now, all life we knew about on Earth was made up of six components: carbon, hydrogen, nitrogen, oxygen, phosphorus and sulfur.   A few scientist has suggested there may be other combinations, but we had not found any that did.

Until now, that is.  This week, Nasa Announced:

Researchers conducting tests in the harsh environment of Mono Lake in California have discovered the first known microorganism on Earth able to thrive and reproduce using the toxic chemical arsenic. The microorganism substitutes arsenic for phosphorus in its cell components.

Phosphorus is a critical part of cellular structure.  It is part of the chemical makeup or RNA and DNA.  Phosphorus is required in the molecules for carrying energy in cells.  And it is part of the material for cell membranes. 

Arsenic is chemically similar to phosphorus.  This causes major problems with most life on Earth since it is able to bind with other chemicals disrupting metabolic pathways.  While scientist have found microbes which can breathe arsenic, this is the first microbe discovered which is building parts of itself using arsenic. 

The search for life beyond Earth has largely focused on looking for the six essential components in an area where they can readily mix as they have here on Earth, in liquid water.  Certainly, the search will now go beyond the primary six.

"If something here on Earth can do something so unexpected, what else can life do that we haven’t seen yet?"

-  Felisa Wolfe-Simon, a NASA Astrobiology Research Fellow in residence at the U.S. Geological Survey in Menlo Park, Calif., and the research team’s lead scientist.

The announcement just published in Nature and reported in Gizmodo this way, “new observations on the red end of the optical spectrum at the W. M. Keck Observatory in Hawaii show an overwhelming population of red dwarfs in eight massive nearby elliptical galaxies. The team has discovered that these galaxies hold twenty times more red dwarfs than the Milky Way.”Van Dokkum says that "there are possibly trillions of Earths orbiting these stars" which are "typically more than 10 billion years old." According to him, that’s long enough for complex life to evolve, which is "one reason why people are interested in this type of star."

Carl Sagan explains why life and in particular intelligent life is more likely with the discovery of more stars similar to our Sun and more combinations for how life can form.

Myogen GlaxoSmithKline agree to joint investment up to $100 million

Filed in Biotechnology | Colorado

GlaxoSmithKline to invest in Myogen
Westminster-based Myogen Inc. said Monday it will receive as much as $100 million from GlaxoSmithKline, as the drugmakers work together on two medicines that treat a lung condition.

Both drugs target pulmonary arterial hypertension, which affects about 200,000 people and, when untreated, can lead to heart failure.

Can open source revolutionise biotech?

Filed in Biotechnology | Healthcare

Economist.com | Biotechnology

THE computing industry has been transformed by open-source software, threatening business models while creating lucrative opportunities for some firms. Might the same happen in biotechnology? In a paper published in Nature on February 10th, a group of researchers describe a way to transfer genes into plants that bypasses the now most commonly used technique, agrobacterium transformation, which is protected by hundreds of patents. The new process may provide an alternative method of modifying certain types of crops in order to, say, improve harvests. But what makes the invention particularly notable is that the authors, affiliated with CAMBIA, a non-profit biotech research group in Australia, have made the procedure free for use under a novel “open-source” licence.

This licence allows people to commercialise products based on the procedure. All that is required is that improvements to the technique itself be shared, to the benefit of all users. This should make it easier for companies and researchers in poor countries to use agricultural gene-transfer technology, which today’s patent-licensing approach impedes.

‘The idea is to try to craft a system so that we have a different way to do business,’ says Richard Jefferson, the head of CAMBIA and a co-author of the paper. ‘This is a demonstration of a way forward for an innovation business model,’ he says, which could help unleash creativity in poorer countries. This week, the group also unveiled a website, BioForge.net, to help biotech researchers to collaborate, much as SourceForge.net is a nexus for open-source software development.

Although open-source approaches have already been used in biotech-related computing (called bioinformatics) and database sharing, CAMBIA’s licence represents an actual technique being provided in an open-source form. It is part of a broader push towards open practices in the life sciences. For example, Science Commons, an offshoot of Creative Commons (which provides less restrictive copyright licences to authors), is preparing to develop open licences later this year. “

10 Emerging Technologies That Will Change Your World

Filed in Biotechnology | Economy | Healthcare | Technology

Technology Review unveils its annual selection of hot new technologies about to affect our lives in revolutionary ways—and profiles the innovators behind them.

Universal Translation
Synthetic Biology
Nanowires
Bayesian Machine Learning
T-Rays
Distributed Storage
RNA Interference
Power Grid Control
Microfluidic Optical Fibers
Personal Genomics

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